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Thalidomide-5-OH

CAS No. 64567-60-8

Thalidomide-5-OH ( —— )

产品货号. M24660 CAS No. 64567-60-8

Thalidomide-5-OH is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥235 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Thalidomide-5-OH
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Thalidomide-5-OH is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.
  • 产品描述
    Thalidomide-5-OH is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    64567-60-8
  • 分子量
    274.2
  • 分子式
    C13H10N2O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO : 60 mg/mL (218.80 mM; Need ultrasonic)
  • SMILES
    Oc(cc1)cc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Megan G Marks, et al. Effects of Putative Hydroxylated Thalidomide Metabolites on Blood Vessel Density in the Chorioallantoic Membrane (CAM) Assay and on Tumor and Endothelial Cell Proliferation. Biol Pharm Bull. 2002 May;25(5):597-604.
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