
Tetroquinone
CAS No. 319-89-1
Tetroquinone ( Tetroquinone | Tetroquinona | Tetroquinonum )
产品货号. M14040 CAS No. 319-89-1
四羟基-1,4-苯醌,也称为四羟基-对苯醌、四羟基苯醌或四羟基醌(THBQ,THQ),是一种有机化合物,化学式为C6O2(OH)4。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
50MG | ¥259 | 有现货 |
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100MG | ¥405 | 有现货 |
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200MG | ¥551 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Tetroquinone
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述四羟基-1,4-苯醌,也称为四羟基-对苯醌、四羟基苯醌或四羟基醌(THBQ,THQ),是一种有机化合物,化学式为C6O2(OH)4。
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产品描述Tetrahydroxy-1,4-benzoquinone, also called tetrahydroxy-p-benzoquinone, tetrahydroxybenzoquinone, or tetrahydroxyquinone (THBQ, THQ), is an organic compound with formula C6O2(OH)4. Its molecular structure consists of a cyclohexadiene ring with four hydroxyl groups and two ketone groups in opposite (para) positions.
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体外实验Tetrahydroxyquinone (100-500 μM; 24 hours; HL60 cells) treatment shows cytotoxic for HL60 leukaemia cells by total protein content (IC50 of 20 μM), phosphatase activity (IC50 of 40 μM), or by MTT assay (IC50 of 45 μM). Tetrahydroxyquinone is an efficient inducer of ROS production in HL60 leukaemia cells. Tetrahydroxyquinone efficiently activates caspase 3 in concentration in excess of 25 μM, stimulates DNA fragmentation at the same concentration and provoke phosphatidylserine exposure. Tetrahydroxyquinone induces the release of cytochrome c from the mitochondria at concentration as low as 25 μM. Tetrahydroxyquinone treatment also causes increase of phosphorylation of Ser473 in protein kinase B (the Bad kinase for Ser112). Cell Viability Assay Cell Line:HL60 leukaemia cells Concentration:100 μM, 200 μM, 300 μM, 400 μM, 500 μM Incubation Time:24 hours Result:Showed cytotoxic for HL60 leukaemia cells.
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体内实验——
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同义词Tetroquinone | Tetroquinona | Tetroquinonum
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通路Others
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靶点Other Targets
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受体Others
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研究领域Cancer
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适应症——
化学信息
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CAS Number319-89-1
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分子量172.09
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分子式C6H4O6
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纯度>98% (HPLC)
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溶解度DMSO: 10 mM
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SMILESO=C1C(O)=C(O)C(C(O)=C1O)=O
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化学全称2,5-Cyclohexadiene-1,4-dione, 2,3,5,6-tetrahydroxy-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Lou K, et al. J Am Chem Soc. 2010 Dec 15; 132(49):17635-4
产品手册




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