Tenatoprazole ( TU-199 | Tenatoprazole | Ulsacare | Protop )

产品货号. M17835 CAS No. 113712-98-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Tenatoprazole
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

替那拉唑是质子泵抑制剂 (PPI) 类的前药，可以抑制质子转运 (IC50: 3.2 μM)。
产品描述

Tenatoprazole, also known as TU-199, is a proton pump inhibitor drug candidate that was undergoing clinical testing as a potential treatment for reflux oesophagitis and peptic ulcer. Tenatoprazole has an imidazopyridine ring in place of the benzimidazole moiety found in other proton pump inhibitors, and has a half-life about seven times longer than other PPIs.
体外实验

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体内实验

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同义词

TU-199 | Tenatoprazole | Ulsacare | Protop
通路

Others
靶点

Other Targets
受体

Proton pump
研究领域

Inflammation/Immunology
适应症

——

CAS Number

113712-98-4
分子量

346.4
分子式

C16H18N4O3S
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 50 mg/mL (144.34 mM)
SMILES

COc1ccc2[nH]c(nc2n1)S(=O)Cc1c(C)c(OC)c(C)cn1
化学全称

5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-imidazo[4,5-b]pyridine

1. Shin JM, et al. Biochem Pharmacol, 2006, 71(6), 837-849.

计算器

产品手册

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