Tecovirimat

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Tecovirimat (ST-246, Tpoxx) 是一种有效的、口服生物可利用的、一流的正痘病毒出口抑制剂，针对一组正痘病毒的 EC50 为 0.01-0.6 uM。

Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxviruses; ST-246 is active against multiple orthopoxviruses, including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), and variola viruse; inhibits the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping.Other Indication Approved.

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ST-246 | ST246 | Tpoxx

Others

Other Targets

Other Targets

Other Indications

Other Disease

869572-92-9

376.335

C19H15F3N2O3

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (265.72 mM)

O=C(NN(C(C1C2C(C3)C3C(C=C2)C41)=O)C4=O)C5=CC=C(C(F)(F)F)C=C5

4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop(f)isoindol-2(1H)-yl)-benzamide

(-20℃)

With Ice Pack

≥ 2 years