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Tecovirimat

CAS No. 869572-92-9

Tecovirimat ( ST-246;ST246;Tpoxx )

产品货号. M16317 CAS No. 869572-92-9

Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxvirusesu.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Tecovirimat
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxvirusesu.
  • 产品描述
    Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxviruses; ST-246 is active against multiple orthopoxviruses, including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), and variola viruse; inhibits the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping.Other Indication Approved
  • 同义词
    ST-246;ST246;Tpoxx
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Other Targets
  • 研究领域
    Other Indications
  • 适应症
    Other Disease

化学信息

  • CAS Number
    869572-92-9
  • 分子量
    376.34
  • 分子式
    C19H15F3N2O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    O=C(NN(C(C1C2C(C3)C3C(C=C2)C41)=O)C4=O)C5=CC=C(C(F)(F)F)C=C5
  • 化学全称
    4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop(f)isoindol-2(1H)-yl)-benzamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Yang G, et al. J Virol. 2005 Oct;79(20):13139-49.
2. Quenelle DC, et al. Antimicrob Agents Chemother. 2007 Feb;51(2):689-95.
3. Bailey TR, et al. J Med Chem. 2007 Apr 5;50(7):1442-4.
4. Quenelle DC, et al. Antimicrob Agents Chemother. 2007 Nov;51(11):4118-24.
产品手册
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