TXNIP-IN-1

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

TXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease.

TXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease.(In Vitro):In monocytes, TXNIP-IN-1 (1.25-5 μM) reduces HG-induced expression of TNF. TXNIP-IN-1 bocks high glucose (HG-induced) TXNIP-TRX complex formation. TXNIP-IN-1 (5 μM; 16-72 hours) inhibits c-TRX interaction in THP1 cells cultured in 25mM glucose. TXNIP-IN-1 targets TXNIP mRNA in human pancreatic islets. In THP1 cells, TXNIP-IN-1 (1.25-5 μM; 72 hours) inhibits TXNIP mRNA expression. TXNIP-IN-1 (0.3-10 μM; 72 hours) inhibits TXNIP mRNA expression in murine RAW macrophages. In MIN6 cells, TXNIP-IN-1 (5-20 μM; 72 hours) decreases TXNIP but not TNF-alpha mRNA levels. TXNIP-IN-1 (0.62-5 μM; 72 hours) affects TXNIP and TNF-alpha mRNA expression in the human pancreas 1.1B4 beta cells.

——

Others

Other Targets

——

——

——

1268955-50-5

248.2

C12H12N2O4

>98% (HPLC)

——

CC(C)C(N1C(=O)c2ccncc2C1=O)C(O)=O

——

(-20℃)

With Ice Pack

≥ 2 years