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TUG-469
CAS No. 1236109-67-3
TUG-469 ( TUG469 | TUG 469 )
产品货号. M28019 CAS No. 1236109-67-3
TUG-469 是一种有效的游离脂肪酸 1 受体激动剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥332 | 有现货 |
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| 10MG | ￥535 | 有现货 |
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| 25MG | ￥1004 | 有现货 |
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| 50MG | ￥1596 | 有现货 |
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| 100MG | ￥2689 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称TUG-469
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述TUG-469 是一种有效的游离脂肪酸 1 受体激动剂。
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产品描述TUG-469 is an effective free fatty acid 1 receptor agonist.
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体外实验TUG-469 (0-10 μM) shows efficacy to hFFA1 with a pEC50 value of 7.73.TUG-469 (10 μM) increases the insulin secretion under 10 mM glucose stimulation.TUG-469 (0-100 μM) is >200-fold selective for FFA1 over FFA4 with EC50 values of 19 nM and 4.4 μM for FFA1 and FFA4, respectively.TUG-469 (5 μM; 30 min) significantly increases insulin secretion of INS-1 cells with the presence of high glucose concentration (16.7 mM).
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体内实验TUG-469 (5 mg/kg; i.p.; 60 and 90 min after glucose administration) affects blood glucose level. Animal Model:Male NZO mice with glucose administration Dosage:5 mg/kg Administration:Intraperitoneal injection; 5 mg/kg; 60 and 90 min after glucose administration Result:Reduced the blood glucose level.
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同义词TUG469 | TUG 469
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通路Others
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靶点Other Targets
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受体Influenza virus|neuroprotection|Antifection
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研究领域——
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适应症——
化学信息
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CAS Number1236109-67-3
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分子量345.442
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分子式C23H23NO2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (289.49 mM)
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SMILESCc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Jung JW, et al. Isoprenylated flavonoids from the root bark of Morus alba and their hepatoprotective and neuroprotective activities. Arch Pharm Res. 2015 Nov;38(11):2066-75.
产品手册
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