TT01001

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

TT01001 是 mitoNEET 的选择性激动剂，通过改善线粒体功能障碍来减少氧化应激损伤和神经元凋亡。 TT01001可用于有关治疗II型糖尿病的研究。

TT01001 is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 can be used in studies about the treatment of type II diabetes.(In Vivo):In type II diabetes model db/db mice, TT01001 improved hyperglycemia, hyperlipidemia, and glucose intolerance, and its efficacy was equivalent to that of pioglitazone, without the pioglitazone-associated weight gain. Mitochondrial complex II + III activity of the skeletal muscle was significantly increased in db/db mice. TT01001 significantly suppressed the elevated activity of the complex II + III.

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TT-01001 | TT 01001 | Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate

Others

Other Targets

RIP2

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1022367-69-6

376.3

C15H19Cl2N3O2S

>98% (HPLC)

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CCOC(=O)N1CCC(CC1)NC(=S)Nc1cc(Cl)cc(Cl)c1

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(-20℃)

With Ice Pack

≥ 2 years