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TRi-1

CAS No. 246020-68-8

TRi-1 ( —— )

产品货号. M20217 CAS No. 246020-68-8

TRi-1 is irreversible inhibitor of?cytosolic thioredoxin reductase 1 (TXNRD1) with an?IC50?of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥778 有现货
5MG ¥1191 有现货
10MG ¥1847 有现货
25MG ¥3062 有现货
50MG ¥4358 有现货
100MG ¥6302 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    TRi-1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    TRi-1 is irreversible inhibitor of?cytosolic thioredoxin reductase 1 (TXNRD1) with an?IC50?of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy.
  • 产品描述
    TRi-1 is irreversible inhibitor of?cytosolic thioredoxin reductase 1 (TXNRD1) with an?IC50?of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    TXNRD1
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    246020-68-8
  • 分子量
    328.72
  • 分子式
    C12H9ClN2O5S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:62.5 mg/mL?(190.13 mM)
  • SMILES
    COc1ccc(c(n1)S(=O)(=O)c1ccc(Cl)cc1)[N+]([O-])=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Stafford WC et al. Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy. Sci Transl Med. 2018 Feb 14;10(428). pii: eaaf7444.
产品手册
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