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TM5441
CAS No. 1190221-43-2
TM5441 ( TM-5441;BMS790052; EBP883 )
产品货号. M17864 CAS No. 1190221-43-2
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor 1 (PAI-1).
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥389 | 有现货 |
|
| 5MG | ￥640 | 有现货 |
|
| 10MG | ￥988 | 有现货 |
|
| 25MG | ￥2130 | 有现货 |
|
| 50MG | ￥3993 | 有现货 |
|
| 100MG | ￥5678 | 有现货 |
|
| 500MG | ￥11826 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称TM5441
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor 1 (PAI-1).
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产品描述TM-5441, also known as EBP 883 and BMS-790052, is a potent plasminogen activator inhibitor-1 (PAI-1). TM-5441 inhibits several tumor cell lines with IC50 values between 9.7 and 60.3 μM. TM5441 protects against high-fat diet-induced obesity and adipocyte injury in mice.
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同义词TM-5441;BMS790052; EBP883
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通路Others
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靶点Other Targets
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受体PAI-1
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研究领域——
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适应症——
化学信息
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CAS Number1190221-43-2
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分子量428.83
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分子式C21H17ClN2O6
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纯度98%
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溶解度DMSO : ≥ 300 mg/mL; 699.59 mM
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SMILESO=C(O)c3cc(Cl)ccc3NC(=O)COCC(=O)Nc1cccc(c1)c2ccco2
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化学全称5-chloro-2-(2-(2-((3-(furan-3-yl)phenyl)amino)-2-oxoethoxy)acetamido)benzoic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Placencio VR, et al. Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity. PLoS One. 2015 Jul 24;10(7):e0133786.
产品手册
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