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首页- Products - Others - Other Targets - TM-N1324

TM-N1324

CAS No. 1144477-35-9

TM-N1324 ( —— )

产品货号. M26846 CAS No. 1144477-35-9

TM-N1324 is a GPR39 agonist. TM-N1324 activates human GPR39 with high efficacy and potencies of 280 nM and 9 nM in the absence and presence of Zn2+, respectively.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ￥502 有现货
5MG ￥786 有现货
10MG ￥1531 有现货
25MG ￥3345 有现货
50MG ￥5006 有现货
100MG ￥7120 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
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生物学信息

  • 产品名称
    TM-N1324
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    TM-N1324 is a GPR39 agonist. TM-N1324 activates human GPR39 with high efficacy and potencies of 280 nM and 9 nM in the absence and presence of Zn2+, respectively.
  • 产品描述
    TM-N1324 is a GPR39 agonist. TM-N1324 activates human GPR39 with high efficacy and potencies of 280 nM and 9 nM in the absence and presence of Zn2+, respectively. TM-N1324 has similar potencies to murine GPR39 with EC50s of 180 nM and 5 nM, respectively.(In Vitro):Measurements of somatostatin confirms that the GPR39 agonist TM-N1324 increases somatostatin release by 53%. TM-N1324 is found to have promising in vitro ADME properties. TM-N1324 has reasonably good aqueous solubility (65 μM at pH 7.0).
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    BTK
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1144477-35-9
  • 分子量
    397.8
  • 分子式
    C18H13ClFN7O
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Cc1nn(c2N=C(O)CC(c12)c1ccc(F)cc1Cl)-c1ncnc2[nH]cnc12
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Valeria Di Battista, et al. Genetics and Pathogenetic Role of Inflammasomes in Philadelphia Negative Chronic Myeloproliferative Neoplasms: A Narrative Review. Int J Mol Sci
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