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TED-347

CAS No. 2378626-29-8

TED-347 ( —— )

产品货号. M21960 CAS No. 2378626-29-8

TED-347 is an?irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥940 有现货
10MG ¥1596 有现货
25MG ¥3216 有现货
50MG ¥4836 有现货
100MG ¥7031 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    TED-347
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    TED-347 is an?irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
  • 产品描述
    TED-347 is an?irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    TEAD4-Yap1
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2378626-29-8
  • 分子量
    313.7
  • 分子式
    C15H11ClF3NO
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:64 mg/ml(204.02 mM)
  • SMILES
    FC(F)(F)c1cccc(Nc2ccccc2C(=O)CCl)c1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Khuchtumur Bum-Erdene, et al. Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD?Yap Protein-Protein Interaction. Cell Chem Biol. 2019 Mar 21;26(3):378-389.e13.
产品手册
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