TCA-1 ( TCA1 )

产品货号. M16276 CAS No. 864941-32-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

TCA-1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A small molecule with activity against drug-resistant and persistent tuberculosis; shows bactericidal activity against nonreplicating Mtb in vitro and is efficacious in acute and chronic Mtb infection mouse models.
产品描述

A small molecule with activity against drug-resistant and persistent tuberculosis; shows bactericidal activity against nonreplicating Mtb in vitro and is efficacious in acute and chronic Mtb infection mouse models; down-regulates genes known to be involved in Mtb persistence; inhibits DprE1 and MoeW, enzymes involved in cell wall and molybdenum cofactor biosynthesis.
同义词

TCA1
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibacterial
研究领域

——
适应症

——

CAS Number

864941-32-2
分子量

375.42
分子式

C16H13N3O4S2
纯度

>98% (HPLC)
溶解度

DMSO: Soluble （ < 1 mg/ml refers to the product slightly soluble or insoluble )
SMILES

CCOC(=O)NC(=O)C1=C(SC=C1)NC(=O)C2=NC3=CC=CC=C3S2
化学全称

ethyl (2-(benzo[d]thiazole-2-carboxamido)thiophene-3-carbonyl)carbamate

1. Wang F, et al. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2510-7.

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