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TBOPP

CAS No. 1996629-79-8

TBOPP ( —— )

产品货号. M22123 CAS No. 1996629-79-8

TBOPP is a selective DOCK1 inhibitor (IC50 : 8.4 μM), with anti-tumor activity for broader types of tumors.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥3021 有现货
10MG ¥3831 有现货
25MG ¥6294 有现货
50MG ¥8829 有现货
100MG ¥11826 有现货
500MG ¥23733 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    TBOPP
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    TBOPP is a selective DOCK1 inhibitor (IC50 : 8.4 μM), with anti-tumor activity for broader types of tumors.
  • 产品描述
    TBOPP is a selective DOCK1 inhibitor (IC50 : 8.4 μM), with anti-tumor activity for broader types of tumors. TBOPP as a selective inhibitor of DOCK1.?TBOPP dampened DOCK1-mediated invasion, macropinocytosis, and survival under the condition of glutamine deprivation without impairing the biological functions of the closely related DOCK2 and DOCK5 proteins.TBOPP treatment suppressed cancer metastasis and growth in vivo in mice.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    DOCK1;DOCK1 DHR-2 domain
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1996629-79-8
  • 分子量
    490.49
  • 分子式
    C24H21F3N2O4S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:120 mg/mL (244.65 mM; Need ultrasonic)
  • SMILES
    FC(F)(F)c1cccc(c1)-c1ccc(cc1)C(=O)Cn1cc(ccc1=O)S(=O)(=O)N1CCCC1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Tajiri H, et al. Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCKCell Rep. 2017 May 2;19(5):969-980.
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