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TBA-354

CAS No. 1257426-19-9

TBA-354 ( TBA354 )

产品货号. M11059 CAS No. 1257426-19-9

TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥365 有现货
5MG ¥583 有现货
10MG ¥988 有现货
25MG ¥1798 有现货
50MG ¥2989 有现货
100MG ¥4447 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    TBA-354
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv.
  • 产品描述
    TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv; maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates, demonstrates superior potency and pharmacokinetic profile compared with PA-824, 5 to 10 times more potent than PA-824.Bacterial Infection Phase 1 Clinical
  • 同义词
    TBA354
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Others
  • 研究领域
    Infection
  • 适应症
    Bacterial Infection

化学信息

  • CAS Number
    1257426-19-9
  • 分子量
    436.34
  • 分子式
    C19H15F3N4O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: ≥ 46 mg/mL
  • SMILES
    O=[N+](C1=CN2C(OC[C@@H](OCC3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)N=C3)C2)=N1)[O-]
  • 化学全称
    5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[6-[4-(trifluoromethoxy)phenyl]-3-pyridinyl]methoxy]-, (6S)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Kmentova I, et al. J Med Chem. 2010 Dec 9;53(23):8421-39.
2. Upton AM, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):136-44.
3. Tasneen R, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):129-35.
产品手册
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