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TBA-354
CAS No. 1257426-19-9
TBA-354 ( TBA354 )
产品货号. M11059 CAS No. 1257426-19-9
TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥365 | 有现货 |
|
| 5MG | ￥583 | 有现货 |
|
| 10MG | ￥988 | 有现货 |
|
| 25MG | ￥1798 | 有现货 |
|
| 50MG | ￥2989 | 有现货 |
|
| 100MG | ￥4447 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称TBA-354
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv.
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产品描述TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv; maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates, demonstrates superior potency and pharmacokinetic profile compared with PA-824, 5 to 10 times more potent than PA-824.Bacterial Infection Phase 1 Clinical
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同义词TBA354
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通路GPCR/G Protein
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靶点Antibacterial
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受体Others
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研究领域Infection
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适应症Bacterial Infection
化学信息
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CAS Number1257426-19-9
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分子量436.34
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分子式C19H15F3N4O5
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 46 mg/mL
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SMILESO=[N+](C1=CN2C(OC[C@@H](OCC3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)N=C3)C2)=N1)[O-]
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化学全称5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[6-[4-(trifluoromethoxy)phenyl]-3-pyridinyl]methoxy]-, (6S)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Kmentova I, et al. J Med Chem. 2010 Dec 9;53(23):8421-39.
2. Upton AM, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):136-44.
3. Tasneen R, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):129-35.
2. Upton AM, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):136-44.
3. Tasneen R, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):129-35.
产品手册
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