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Sulfopin
CAS No. 2451481-08-4
Sulfopin ( PIN1-3 )
产品货号. M24127 CAS No. 2451481-08-4
Sulfopin 是 Pin1 的高选择性共价抑制剂，表观 Ki 为 17nM。 Sulfopin 可在体内阻断 Myc 驱动的肿瘤。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥373 | 有现货 |
|
| 5MG | ￥616 | 有现货 |
|
| 10MG | ￥1021 | 有现货 |
|
| 25MG | ￥2098 | 有现货 |
|
| 50MG | ￥3378 | 有现货 |
|
| 100MG | ￥5038 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Sulfopin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Sulfopin 是 Pin1 的高选择性共价抑制剂，表观 Ki 为 17nM。 Sulfopin 可在体内阻断 Myc 驱动的肿瘤。
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产品描述Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
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体外实验Cell Proliferation Assay Cell Line:Kuramochi, MDA-MB-468, NGP, NBL-S, MDA-MB-468 cells Concentration:1, 2.5 μM Incubation Time:4,6, 8 days Result:Showed variation in antiproliferative effects across cancer cell lines Kuramochi, MDA-MB-468, NGP and NBL-S, with the most pronounced sensitivity observed in MDA-MB-468 cells.
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体内实验——
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同义词PIN1-3
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通路Others
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靶点Other Targets
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受体Pin1
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研究领域——
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适应症——
化学信息
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CAS Number2451481-08-4
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分子量281.8
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分子式C11H20ClNO3S
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纯度>98% (HPLC)
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溶解度DMSO : 90 mg/mL (319.38 mM; Need ultrasonic)
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SMILESO=C(N(CC(C)(C)C)C(CC1)CS1(=O)=O)CCl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Dubiella C , Pinch B J , Koikawa K , et al. Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo[J]. Nature Chemical Biology.
产品手册
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