Spathulenol
CAS No. 6750-60-3
Spathulenol ( —— )
产品货号. M31040 CAS No. 6750-60-3
Spathulenol has immunomodulatory effect. Spathulenol shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥3751 | 有现货 |
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50MG | 获取报价 | 有现货 |
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100MG | 获取报价 | 有现货 |
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生物学信息
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产品名称Spathulenol
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Spathulenol has immunomodulatory effect. Spathulenol shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway.
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产品描述Spathulenol has immunomodulatory effect. Spathulenol shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway; it presents moderate or low cytotoxicity with IC50 higher than 6uM, it is a good candidate to be used in combination chemotherapy of MDR cancer.
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体外实验Spathulenolexhibits ahigh antioxidant activity s in the DPPH and MDA system,exhibits significant DPPH free radical activity, with IC50 values of85.60 μg/mL.
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体内实验Spathulenol (oral administration; 300 mg/kg)shows a significant inhibition in the Cg-induced mice paw oedema and pleurisy model.In a spontaneous lipoperoxidation rat brain homogenate model, when incubated in controlled temperature and.oxygenation conditions, PG-1 exhibits a high activity with an IC50 value of 26.13 μg/mL, respectively, which is comparable to a commercial antioxidant BHT (38.41 μg/mL), Thus, PG-1 contributes to a decrease in the generation of MDA,which is a toxic product resulting from the degradation of the cell membrane by lipid peroxidation, causing cell ruptures and mutations.
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number6750-60-3
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分子量220.4
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分子式C15H24O
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (453.82 mM)
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years