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Smurf1-IN-A01

CAS No. 1007647-73-5

Smurf1-IN-A01 ( A01 )

产品货号. M23212 CAS No. 1007647-73-5

Smurf1-IN-A01 is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥365 有现货
5MG ¥583 有现货
10MG ¥988 有现货
25MG ¥2001 有现货
50MG ¥3208 有现货
100MG ¥4771 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Smurf1-IN-A01
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Smurf1-IN-A01 is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM).
  • 产品描述
    Smurf1-IN-A01 is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM). It increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.
  • 同义词
    A01
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Smurf1
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1007647-73-5
  • 分子量
    512.9
  • 分子式
    C22H20ClF3N4O3S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:62.5 mg/mL (121.85 mM; Need ultrasonic)
  • SMILES
    CC1=CC=NN1C2=CC=C(C=C2)C(=O)N3CCN(CC3)S(=O)(=O)C4=CC(=C(C=C4)Cl)C(F)(F)F
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Cao Y, et al. Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation. Sci Rep. 2014 May 14;4:4965.
产品手册
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