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Silodosin
CAS No. 160970-54-7
Silodosin ( KAD 3213;KMD 3213 )
产品货号. M12319 CAS No. 160970-54-7
A highly potent, uroselective α1a-adrenoceptor antagonist with Ki of 36 pM; displays 583- and 56-fold lower potency against α1b and α1d respectors, respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥259 | 有现货 |
|
| 10MG | ￥421 | 有现货 |
|
| 25MG | ￥616 | 有现货 |
|
| 50MG | ￥737 | 有现货 |
|
| 100MG | ￥875 | 有现货 |
|
| 200MG | ￥1094 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Silodosin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A highly potent, uroselective α1a-adrenoceptor antagonist with Ki of 36 pM; displays 583- and 56-fold lower potency against α1b and α1d respectors, respectively.
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产品描述A highly potent, uroselective α1a-adrenoceptor antagonist with Ki of 36 pM; displays 583- and 56-fold lower potency against α1b and α1d respectors, respectively; inhibits norepinephrine-induced increases intracellular Ca2+ concentrations in CHO cells with IC50 of 0.32 nM; inhibits intraurethral pressure (IUP) response in vivo.Other Indication Approved
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同义词KAD 3213;KMD 3213
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通路Angiogenesis
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靶点Adrenergic Receptor
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受体β-adrenergicreceptor
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研究领域Other Indications
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适应症Other Disease
化学信息
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CAS Number160970-54-7
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分子量495.53
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分子式C25H32F3N3O4
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESO=C(C1=CC(C[C@H](NCCOC2=CC=CC=C2OCC(F)(F)F)C)=CC3=C1N(CCCO)CC3)N
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化学全称1H-Indole-7-carboxamide, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Shibata K, et al. Mol Pharmacol. 1995 Aug;48(2):250-8.
2. Yamagishi R, et al. Eur J Pharmacol. 1996 Nov 7;315(1):73-9.
3. Yamada S, et al. Life Sci. 1998;62(17-18):1585-9.
4. Akiyama K, et al. J Pharmacol Exp Ther. 1999 Oct;291(1):81-91.
2. Yamagishi R, et al. Eur J Pharmacol. 1996 Nov 7;315(1):73-9.
3. Yamada S, et al. Life Sci. 1998;62(17-18):1585-9.
4. Akiyama K, et al. J Pharmacol Exp Ther. 1999 Oct;291(1):81-91.
产品手册
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