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Shield-1

CAS No. 914805-33-7

Shield-1 ( —— )

产品货号. M24959 CAS No. 914805-33-7

Shield-1 is a specific, high-affinity and cell-permeant ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥3013 有现货
10MG ¥4795 有现货
25MG ¥7622 有现货
50MG ¥10368 有现货
100MG ¥13932 有现货
500MG ¥27783 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Shield-1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Shield-1 is a specific, high-affinity and cell-permeant ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein.
  • 产品描述
    Shield-1 is a specific, high-affinity and cell-permeant ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    FKBP
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    914805-33-7
  • 分子量
    748.9
  • 分子式
    C42H56N2O10
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:250 mg/mL (333.82 mM)
  • SMILES
    O=C([C@H]1N(C([C@H](C2=CC(OC)=C(OC)C(OC)=C2)CC)=O)CCCC1)O[C@@H](C3=CC=CC(OCCN4CCOCC4)=C3)CCC5=CC=C(OC)C(OC)=C5
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Schoeber JP, et al. Conditional fast expression and function of multimeric TRPV5 channels using Shield-1. Am J Physiol Renal Physiol. 2009 Jan;296(1):F204-11.
产品手册
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