Sesamol ( —— )

产品货号. M18752 CAS No. 533-31-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Sesamol
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Sesamol could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats.
产品描述

Sesamol could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways and inhibits melanin biosynthesis by down-regulating tyrosinase activity and melanin production via regulation of gene expression of melanogenesis-related proteins through modulation of MITF activity, which promotes phosphorylation of p38 and JNK in melan-a cells.
同义词

——
通路

Others
靶点

Other Targets
受体

AMPK
研究领域

Inflammation/Immunology
适应症

——

1. Wu XL, et al. Inflamm Res. 2015 Aug;64(8):577-88.

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