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Sertindole

CAS No. 106516-24-9

Sertindole ( Lu 23-174 )

产品货号. M20510 CAS No. 106516-24-9

Sertindole is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D 5-HT2A and 5-HT2C (Kds = 2.7 20 0.14 and 6 nM respectively).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥365 有现货
10MG ¥478 有现货
25MG ¥1183 有现货
50MG ¥2349 有现货
100MG ¥3200 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Sertindole
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Sertindole is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D 5-HT2A and 5-HT2C (Kds = 2.7 20 0.14 and 6 nM respectively).
  • 产品描述
    Sertindole is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D 5-HT2A and 5-HT2C (Kds = 2.7 20 0.14 and 6 nM respectively)
  • 同义词
    Lu 23-174
  • 通路
    GPCR/G Protein
  • 靶点
    Dopamine Receptor
  • 受体
    D2;5-HT
  • 研究领域
    Metabolic Disease
  • 适应症
    Chronic obstructive pulmonary disease

化学信息

  • CAS Number
    106516-24-9
  • 分子量
    440.94
  • 分子式
    C24H26ClFN4O
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:50 mg/mL (113.39 mM)
  • SMILES
    Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12
  • 化学全称
    1-[2-[4-[5-chloro-1-(4-fluorophenyl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.MRk A Witten L M Arnt J . Effect of sertindole on extracellular dopamine acetylcholine and glutamate in the medial prefrontal cortex of conscious rats: a comparison with risperidone and exploration of mechanisms involved[J]. Psychopharmacology 2009 206(1):39-49.
产品手册
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