Serlopitant ( VPD-737;MK-0594 )

产品货号. M16236 CAS No. 860642-69-9

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Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Serlopitant
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Serlopitant (VPD-737, MK-0594) is a potent, selective substance P/neurokinin 1 (NK1) receptor for treating chronic pruritus.
产品描述

Serlopitant (VPD-737, MK-0594) is a potent, selective substance P/neurokinin 1 (NK1) receptor for treating chronic pruritus.Alcoholism Discontinued
同义词

VPD-737;MK-0594
通路

GPCR/G Protein
靶点

Neurokinin Receptor
受体

Neurokinin Receptor
研究领域

Neurological Disease
适应症

Alcoholism

CAS Number

860642-69-9
分子量

555.54
分子式

C29H28F7NO2
纯度

>98% (HPLC)
溶解度

——
SMILES

O=C1C=C(N2C[C@@]3([H])CC[C@H](O[C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)[C@@H](C5=CC=C(F)C=C5)[C@]3([H])C2)CC1
化学全称

3-((3aR,4R,5S,7aS)-5-((1R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-4-(4 fluorophenyl)octahydro-2H-isoindol-2-yl)cyclopent-2-en-1-one

1. Yosipovitch G, et al. J Am Acad Dermatol. 2018 May;78(5):882-891.e10.

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