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Sepin-1

CAS No. 163126-81-6

Sepin-1 ( Sepin 1; Sepin1; 2H-Benzimidazole, 2,2-dimethyl-5-nitro-, 1,3-dioxide )

产品货号. M27925 CAS No. 163126-81-6

Sepin-1 is a noncompetitive inhibitor of separase with an IC50 of 14.8 μM. Sepin-1 can inhibit the growth of breast cancer xenograft tumors in mice and human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥648 有现货
10MG ¥1037 有现货
25MG ¥2341 有现货
50MG ¥3872 有现货
100MG ¥5581 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Sepin-1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Sepin-1 is a noncompetitive inhibitor of separase with an IC50 of 14.8 μM. Sepin-1 can inhibit the growth of breast cancer xenograft tumors in mice and human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.
  • 产品描述
    Sepin-1 is a noncompetitive inhibitor of separase with an IC50 of 14.8 μM. Sepin-1 can inhibit the growth of breast cancer xenograft tumors in mice and human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.
  • 同义词
    Sepin 1; Sepin1; 2H-Benzimidazole, 2,2-dimethyl-5-nitro-, 1,3-dioxide
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Endogenous Metabolite
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    163126-81-6
  • 分子量
    223.2
  • 分子式
    C9H9N3O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC1(C)[N+]([O-])=c2ccc(cc2=[N+]1[O-])[N+]([O-])=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.P F Li, et al. [Inhibitory effect of 2-(N-acetyl-methyl amino)-3',4'-methylenedioxyacetyl-aminophene(SY-640) on covalent binding of carcinogenic benzo(a)pyrene with mouse hepatocyte nuclear DNA]. Yao Xue Xue Bao. 1997 Sep;32(9):663-8.
产品手册
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