• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

STM2457

CAS No. 2499663-01-1

STM2457 ( —— )

产品货号. M24139 CAS No. 2499663-01-1

STM2457 is a first-in-class, highly potent, selective and orally active inhibitor of METTL3 . It can be used for the research of acute myeloid leukaemia (AML).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1750 有现货
10MG ¥2827 有现货
25MG ¥4690 有现货
50MG ¥6707 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    STM2457
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    STM2457 is a first-in-class, highly potent, selective and orally active inhibitor of METTL3 . It can be used for the research of acute myeloid leukaemia (AML).
  • 产品描述
    STM2457 is a first-in-class, highly potent, selective and orally active inhibitor of METTL3 . It can be used for the research of acute myeloid leukaemia (AML).
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    METTL3
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2499663-01-1
  • 分子量
    444.5
  • 分子式
    C25H28N6O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:125 mg/mL (281.20 mM; Need ultrasonic)
  • SMILES
    O=C(C(N=C1N2C=CC=C1)=CC2=O)NCC3=CN4C=C(CNCC5CCCCC5)C=CC4=N3
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Wesley Peter Blackaby, et al. Mettl3 inhibitory compounds. WO2020201773A1.
产品手册
关联产品
  • DL-5-Hydroxylysine h...

    DL-5-Hydroxylysine is a racemic mixture of D- and L- enantiomers of 5-hydroxylysine which may be used as potential target markers for radical-induced protein oxidation.

  • PACAP-38 (31-38), hu...

    PACAP-38 (31-38), human, mouse, rat (TFA) demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal.

  • Glyasperin C

    Glyasperin C acts as a partial estrogen antagonist, it shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candidate in the design of skin-whitening agents. Glyasperin C shows potent anti-vancomycin-resistant Enterococci effects (MIC 1.9 × 10-5-4.5 × 10-5 M for E. faecium and E. faecalis).