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STF-62247

CAS No. 315702-99-9

STF-62247 ( STF62247;STF 62247 )

产品货号. M14025 CAS No. 315702-99-9

STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥251 有现货
10MG ¥373 有现货
25MG ¥794 有现货
50MG ¥1377 有现货
100MG ¥2406 有现货
200MG ¥3702 有现货
500MG ¥5978 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    STF-62247
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells.
  • 产品描述
    STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells; induces cytotoxicity and reduces tumor growth in VHL-deficient cells in a HIF-independent manner, PI3K and Golgi trafficking are required as initial signals in STF-62247-induced autophagy.Kidney Cancer Preclinical
  • 同义词
    STF62247;STF 62247
  • 通路
    Autophagy
  • 靶点
    Autophagy
  • 受体
    ER
  • 研究领域
    Cancer
  • 适应症
    Kidney Cancer

化学信息

  • CAS Number
    315702-99-9
  • 分子量
    267.35
  • 分子式
    C15H13N3S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: ≥ 31 mg/mL
  • SMILES
    CC1=CC(NC2=NC(C3=CC=NC=C3)=CS2)=CC=C1
  • 化学全称
    2-Thiazolamine, N-(3-methylphenyl)-4-(4-pyridinyl)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Turcotte S, et al. Cancer Cell. 2008 Jul 8;14(1):90-102.
2. Turcotte S, et al. Autophagy. 2008 Oct;4(7):944-6.
3. Chan DA, et al. Cell Cycle. 2008 Oct;7(19):2987-90.
4.Kozako T, et al. Oncotarget. 2018 Jun 12;9(45):27645-27655.
产品手册
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