ST-034307 ( ST 034307;ST034307 )

产品货号. M11327 CAS No. 133406-29-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

ST-034307
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

ST-034307 (ST 034307, ST034307) is a potent, selective adenylyl cyclase 1 (AC1) with IC50 of 2.3 uM.
产品描述

ST-034307 (ST 034307, ST034307) is a potent, selective adenylyl cyclase 1 (AC1) with IC50 of 2.3 uM; shows no activity against other AC isoforms; inhibits Ca2+-stimulated cAMP accumulation in HEK cells, also inhibits AC1 activity stimulated by forskolin- and Gαs-coupled receptors in HEK-AC1 cells; reduces pain responses in a mouse model of inflammatory pain.
同义词

ST 034307;ST034307
通路

Metabolic Enzyme/Protease
靶点

Adenylate Cyclase
受体

Adenylate Cyclase
研究领域

Neurological Disease
适应症

——

1. Brust TF, et al. Sci Signal. 2017 Feb 21;10(467). pii: eaah5381.

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产品手册

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Small Cardioactive P...

Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively.