SRT3109

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.

SRT3109 is a CXCR2 ligand. CXCR2 ligands are potent chemoattractants for neutrophils and play a key role in the emigration of neutrophils from the blood to sites of tissue inflammation. Moreover, CXCR2 signaling may also regulate neutrophil mobilization from the bone marrow. Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis.

SRT3109; SRT-3109

Others

Other Targets

CXCR2

Inflammation/Immunology

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1204707-71-0

475.53

C18H23F2N5O4S2

98%

DMSO : ≥ 100 mg/mL; 210.29 mM

C[C@H]([C@H](CO)O)Nc1cc(nc(n1)SCc1c(c(ccc1)F)F)NS(=O)(=O)N1CCC1

N-(2-((2,3-difluorobenzyl)thio)-6-(((2R,3R)-3,4-dihydroxybutan-2-yl)amino)pyrimidin-4-yl)azetidine-1-sulfonamide

(-20℃)

With Ice Pack

≥ 2 years