SRT3109 ( SRT3109; SRT-3109 )

产品货号. M17881 CAS No. 1204707-71-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

SRT3109
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.
产品描述

SRT3109 is a CXCR2 ligand. CXCR2 ligands are potent chemoattractants for neutrophils and play a key role in the emigration of neutrophils from the blood to sites of tissue inflammation. Moreover, CXCR2 signaling may also regulate neutrophil mobilization from the bone marrow. Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis.
同义词

SRT3109; SRT-3109
通路

Others
靶点

Other Targets
受体

CXCR2
研究领域

Inflammation/Immunology
适应症

——

CAS Number

1204707-71-0
分子量

475.53
分子式

C18H23F2N5O4S2
纯度

98%
溶解度

DMSO : ≥ 100 mg/mL; 210.29 mM
SMILES

C[C@H]([C@H](CO)O)Nc1cc(nc(n1)SCc1c(c(ccc1)F)F)NS(=O)(=O)N1CCC1
化学全称

N-(2-((2,3-difluorobenzyl)thio)-6-(((2R,3R)-3,4-dihydroxybutan-2-yl)amino)pyrimidin-4-yl)azetidine-1-sulfonamide

计算器

产品手册

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