
SRT3109
CAS No. 1204707-71-0
SRT3109 ( SRT3109 | SRT-3109 )
产品货号. M17881 CAS No. 1204707-71-0
SRT3109 是一种 CXCR2 配体,用于治疗趋化因子介导的疾病和病症。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥1499 | 有现货 |
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5MG | ¥2292 | 有现货 |
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10MG | ¥3418 | 有现货 |
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25MG | ¥5573 | 有现货 |
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50MG | ¥7752 | 有现货 |
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100MG | ¥10368 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称SRT3109
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述SRT3109 是一种 CXCR2 配体,用于治疗趋化因子介导的疾病和病症。
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产品描述SRT3109 is a CXCR2 ligand. CXCR2 ligands are potent chemoattractants for neutrophils and play a key role in the emigration of neutrophils from the blood to sites of tissue inflammation. Moreover, CXCR2 signaling may also regulate neutrophil mobilization from the bone marrow. Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis.
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体外实验SRT3109 (Example 1) is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases.
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体内实验——
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同义词SRT3109 | SRT-3109
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通路Others
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靶点Other Targets
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受体CXCR2
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number1204707-71-0
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分子量475.53
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分子式C18H23F2N5O4S2
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 100 mg/mL; 210.29 mM
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SMILESC[C@H]([C@H](CO)O)Nc1cc(nc(n1)SCc1c(c(ccc1)F)F)NS(=O)(=O)N1CCC1
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化学全称N-(2-((2,3-difluorobenzyl)thio)-6-(((2R,3R)-3,4-dihydroxybutan-2-yl)amino)pyrimidin-4-yl)azetidine-1-sulfonamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册




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