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SR8278

CAS No. 1254944-66-5

SR8278 ( —— )

产品货号. M21127 CAS No. 1254944-66-5

SR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM) blocking activation of the receptor by the synthetic agonist GSK 4112.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1004 有现货
10MG ¥1596 有现货
50MG ¥3726 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    SR8278
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    SR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM) blocking activation of the receptor by the synthetic agonist GSK 4112.
  • 产品描述
    SR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM) blocking activation of the receptor by the synthetic agonist GSK 4112.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    REV-ERBα
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1254944-66-5
  • 分子量
    361.48
  • 分子式
    C18H19NO3S2
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:10mg/ml(27.66mM)
  • SMILES
    CCOC(=O)C1Cc2ccccc2CN1C(=O)c1ccc(SC)s1
  • 化学全称
    ethyl 2-{[5-(methylsulfanyl)thiophen-2-yl]carbonyl}-1234-tetrahydroisoquinoline-3-carboxylate

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Kojetin D Wang Y Kamenecka T M et al. Identification of SR8278 a Synthetic Antagonist of the Nuclear Heme Receptor REV-ERB[J]. Acs Chemical Biology 2011 6(2):131-134.
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