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SR11237
CAS No. 146670-40-8
SR11237 ( BMS-649 )
产品货号. M27716 CAS No. 146670-40-8
SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1531 | 有现货 |
|
| 10MG | ￥2325 | 有现货 |
|
| 25MG | ￥4682 | 有现货 |
|
| 50MG | ￥6747 | 有现货 |
|
| 100MG | ￥9315 | 有现货 |
|
| 500MG | ￥18549 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称SR11237
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.
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产品描述SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.(In Vitro):SR11237 is effective at transactivating a chloramphenicol acetyltransferase reporter gene through RXRs but not retinoic acid receptors in COS-1 cells.(In Vivo):In Sprague-Dawley rats, SR11237 (BMS-649) (25 mg/kg; i.p.) Caused disturbed ossification and bone morphology in rats, including premature growth plate closure and infiltration of ossified tissue through the central epiphysis.
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同义词BMS-649
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通路Others
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靶点Other Targets
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受体Aurora A
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研究领域——
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适应症——
化学信息
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CAS Number146670-40-8
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分子量380.5
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分子式C24H28O4
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纯度>98% (HPLC)
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溶解度——
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SMILESCC1(C)CCC(C)(C)c2cc(ccc12)C1(OCCO1)c1ccc(cc1)C(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Ando R, et al. 3-Cyano-6-(5-methyl-3-pyrazoloamino)pyridines: selective Aurora A kinase inhibitors. Bioorg Med Chem Lett. 2010;20(15):4709-4711.
产品手册
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