SP-8356
CAS No. 1454885-45-0
SP-8356 ( —— )
产品货号. M26459 CAS No. 1454885-45-0
SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147) with anti-atherosclerotic effects.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2130 | 有现货 |
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10MG | ¥3378 | 有现货 |
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25MG | ¥6383 | 有现货 |
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50MG | ¥8667 | 有现货 |
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100MG | ¥11583 | 有现货 |
|
500MG | ¥23409 | 有现货 |
|
1G | 获取报价 | 有现货 |
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生物学信息
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产品名称SP-8356
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147) with anti-atherosclerotic effects.
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产品描述SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147) with anti-atherosclerotic effects.(In Vitro):In a time- and dose-dependent manner, SP-8356 (5-10?μM; 48 hours) inhibits the growth of various types of breast cancer cell lines. SP-8356 (10?μM; 48 hours) increases the percentage of MDA-MB231 cells in the S phase and decreases caspase-3 and cleaved PARP .(In Vivo):In a xenograft mouse model, SP-8356 (10?mg/kg; i.p.; every three days until the 42nd day) inhibits tumor growth . SP-8356 (50 mg/kg; p.o.; daily one day after carotid artery ligation for three weeks) prevents the formation of plaque and attenuates its vulnerability .
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同义词——
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通路Autophagy
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靶点Autophagy
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受体COX-2; ROS
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研究领域——
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适应症——
化学信息
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CAS Number1454885-45-0
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分子量300.4
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分子式C18H20O4
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纯度>98% (HPLC)
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溶解度——
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SMILES[H][C@@]12C[C@@]([H])(C(\C=C\c3cc(O)c(O)c(OC)c3)=CC1=O)C2(C)C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Zhenggang Zhou, et al. PBN Protects NP Cells From AAPH-induced Degenerative Changes by Inhibiting the ERK1/2 Pathway. Connect Tissue Res. 2020 Mar 30;1-10.
产品手册
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