SP-13786
CAS No. 1448440-52-5
SP-13786 ( UAMC-1110 )
产品货号. M21138 CAS No. 1448440-52-5
SP-13786 is an inhibitor of fibroblast activation protein (FAP) (IC50 : 3.2 nM); also inhibits prolyl oligopeptidase (PREP) ( IC50 : 1.8 μM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥1037 | 有现货 |
|
5MG | ¥1717 | 有现货 |
|
10MG | ¥2535 | 有现货 |
|
25MG | ¥4277 | 有现货 |
|
50MG | ¥6180 | 有现货 |
|
100MG | ¥8667 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称SP-13786
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述SP-13786 is an inhibitor of fibroblast activation protein (FAP) (IC50 : 3.2 nM); also inhibits prolyl oligopeptidase (PREP) ( IC50 : 1.8 μM).
-
产品描述SP-13786 is an inhibitor of fibroblast activation protein (FAP) (IC50 : 3.2 nM); also inhibits prolyl oligopeptidase (PREP) ( IC50 : 1.8 μM).
-
同义词UAMC-1110
-
通路Others
-
靶点Other Targets
-
受体FAP
-
研究领域——
-
适应症——
化学信息
-
CAS Number1448440-52-5
-
分子量344.32
-
分子式C17H14F2N4O2
-
纯度>98% (HPLC)
-
溶解度DMSO:100 mg/mL (290.43 mM; Need ultrasonic)
-
SMILESN#CC1CC(F)(F)CN1C(=O)CNC(=O)c1ccnc2ccccc12
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Jansen K Heirbaut L Verkerk R et al. Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)[J]. Journal of Medicinal Chemistry 2014 57(7):3053-3074.
产品手册
关联产品
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
-
7-Troc-paclitaxel
7-Troc-paclitaxel is a precursor of paclitaxel which has anti-tumor activity.
-
alpha-[4-[(1E)-2-Car...
The herbs of Origanum dictamnus.