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SMS2-IN-2
CAS No. 2241838-28-6
SMS2-IN-2 ( SMS2 inhibitors )
产品货号. M20666 CAS No. 2241838-28-6
SMS2-IN-2 is a potent selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50s of 100 and 56 μM for SMS2 and SMS1 respectively). SMS2-IN-2 has anti-chronic inflammatory activity.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1369 | 有现货 |
|
| 5MG | ￥2333 | 有现货 |
|
| 10MG | ￥3637 | 有现货 |
|
| 25MG | ￥5986 | 有现货 |
|
| 50MG | ￥7995 | 有现货 |
|
| 100MG | ￥11259 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称SMS2-IN-2
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述SMS2-IN-2 is a potent selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50s of 100 and 56 μM for SMS2 and SMS1 respectively). SMS2-IN-2 has anti-chronic inflammatory activity.
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产品描述SMS2-IN-2 is a potent selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50s of 100 and 56 μM for SMS2 and SMS1 respectively). SMS2-IN-2 has anti-chronic inflammatory activity.
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同义词SMS2 inhibitors
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通路Others
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靶点Other Targets
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受体SMS2
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研究领域——
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适应症——
化学信息
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CAS Number2241838-28-6
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分子量369.78
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分子式C19H13ClFN3O2
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纯度>98% (HPLC)
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溶解度DMSO:250 mg/mL (676.08 mM)
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SMILESFc1ccc(Cl)c(COc2cccc3onc(Nc4cccnc4)c23)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Mo M Yang J Jiang XCet al.Discovery of 4-Benzyloxybenzo[ d]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in db/ db Mice[J].J Med Chem. 2018 Sep 27;61(18):8241-8254.?
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