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首页- Products - Others - Other Targets - SMS2-IN-2

SMS2-IN-2

CAS No. 2241838-28-6

SMS2-IN-2 ( SMS2 inhibitors )

产品货号. M20666 CAS No. 2241838-28-6

SMS2-IN-2 is a potent selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50s of 100 and 56 μM for SMS2 and SMS1 respectively). SMS2-IN-2 has anti-chronic inflammatory activity.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ￥1369 有现货
5MG ￥2333 有现货
10MG ￥3637 有现货
25MG ￥5986 有现货
50MG ￥7995 有现货
100MG ￥11259 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
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生物学信息

  • 产品名称
    SMS2-IN-2
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    SMS2-IN-2 is a potent selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50s of 100 and 56 μM for SMS2 and SMS1 respectively). SMS2-IN-2 has anti-chronic inflammatory activity.
  • 产品描述
    SMS2-IN-2 is a potent selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50s of 100 and 56 μM for SMS2 and SMS1 respectively). SMS2-IN-2 has anti-chronic inflammatory activity.
  • 同义词
    SMS2 inhibitors
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    SMS2
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2241838-28-6
  • 分子量
    369.78
  • 分子式
    C19H13ClFN3O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:250 mg/mL (676.08 mM)
  • SMILES
    Fc1ccc(Cl)c(COc2cccc3onc(Nc4cccnc4)c23)c1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Mo M Yang J Jiang XCet al.Discovery of 4-Benzyloxybenzo[ d]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in db/ db Mice[J].J Med Chem. 2018 Sep 27;61(18):8241-8254.?
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