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SMS2-IN-1
CAS No. 2098890-15-2
SMS2-IN-1 ( —— )
产品货号. M26453 CAS No. 2098890-15-2
SMS2-IN-1 是一种高度选择性的鞘磷脂合成酶 2 (SMS2) 抑制剂（IC50 为 6.5 nM）。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥3021 | 有现货 |
|
| 50MG | ￥16038 | 有现货 |
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| 100MG | ￥20250 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称SMS2-IN-1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述SMS2-IN-1 是一种高度选择性的鞘磷脂合成酶 2 (SMS2) 抑制剂（IC50 为 6.5 nM）。
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产品描述SMS2-IN-1 is a highly selective inhibitor of sphingomyelin synthase 2 (SMS2)(IC50 of 6.5 nM).(In Vitro):SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 with IC50 of 1000 nM.
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体外实验AS/MS binding experiments are conducted using these SMS2-mutant membrane fractions, SMS2-IN-1 (compound 2) binds to the S217A, H272A, and D276A mutants. S227 and H229 are pivotal amino acid residues for the binding of SMS2-IN-1 to SMS2.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体RXR
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研究领域——
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适应症——
化学信息
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CAS Number2098890-15-2
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分子量681.676
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分子式C34H37F6N3O5
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 27.78 mg/mL (40.75 mM)
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SMILESCN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)c1c(OCCCC2CCN(CC2)C(=O)OC2(C)CC2)c2ccccc2n(C)c1=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Bradley SM, Chan PS, Spertus JA, Kennedy KF, Douglas PS, Patel MR, Anderson HV, Ting HH, Rumsfeld JS, Nallamothu BK. Hospital percutaneous coronary intervention appropriateness and in-hospital procedural outcomes: insights from the NCDR. Circ Cardiovasc Qual Outcomes. 2012 May;5(3):290-7.
产品手册
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