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SMIFH2
CAS No. 340316-62-3
SMIFH2 ( —— )
产品货号. M27714 CAS No. 340316-62-3
SMIFH2 是福尔马林同源 2 (FH2) 结构域抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥324 | 有现货 |
|
| 5MG | ￥518 | 有现货 |
|
| 10MG | ￥786 | 有现货 |
|
| 25MG | ￥1604 | 有现货 |
|
| 50MG | ￥3200 | 有现货 |
|
| 100MG | ￥4755 | 有现货 |
|
| 500MG | ￥9315 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称SMIFH2
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述SMIFH2 是福尔马林同源 2 (FH2) 结构域抑制剂。
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产品描述SMIFH2 is formin homology 2 (FH2) domains inhibitor.
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体外实验SMIFH2 (25 uM; 1-16 hours) induces dynamic cytoskeletal remodelling in U2OS cells. SMIFH2 (25 μM) reduces p300, mDia2 and p53 levels in a proteasome-independent manner.SMIFH2 reduces expression and activity of p53 through a post-transcriptional, proteasome-independent mechanism that influences remodelling of the cytoskeleton. Western Blot Analysis Cell Line:293T, A375, U2OS, and MDA-MB-231 cells Concentration:25 μM Incubation Time:5 hours for 293T, U2OS, MDA-MB-231 cells; 2.5 hours for A375 cells Result:Downregulated mDia2, p53 and p300 protein levels.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体mGluR5
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研究领域——
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适应症——
化学信息
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CAS Number340316-62-3
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分子量377.21
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分子式C15H9BrN2O3S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (331.38 mM)
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SMILESBrc1cccc(c1)N1C(=S)NC(=O)\C(=C/c2ccco2)C1=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Keck TM, et al. A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats. Addict Biol.
产品手册
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