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SGN-2FF

CAS No. 2089647-47-0

SGN-2FF ( —— )

产品货号. M26438 CAS No. 2089647-47-0

SGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1320 有现货
10MG ¥2341 有现货
25MG ¥4682 有现货
50MG ¥6383 有现货
100MG ¥9072 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    SGN-2FF
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    SGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.
  • 产品描述
    SGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.(In Vitro):SGN-2FF is a fucosylation inhibitor, SGN-2FF inhibits cellular fucosylation by depleting the fucosylation substrate GDP-fucose, and by direct inhibition of fucosyltransferases, and leads to the production of fucosylated glycoproteins including antibodies. SGN-2FF activates human T cells in an antigen-dependent manner.(In Vivo):In multiple mouse tumor models, SGN-2FF exhibits antitumor activity. SGN-2FF shows substantial tumor growth delay. SGN-2FF elevates the protective effect of a lymphoma vaccine in a syngeneic mouse model.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Telomerase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2089647-47-0
  • 分子量
    166.1
  • 分子式
    C6H11FO4
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    C[C@@H]1OC(O)[C@@H](F)[C@H](O)[C@@H]1O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Quan Wang J, et al. Discovery of new chromen-4-one derivatives as telomerase inhibitors through regulating expression of dyskerin. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1199-1211.
产品手册
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