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首页- Products - Others - Other Targets - SCH-37370

SCH-37370

CAS No. 117796-52-8

SCH-37370 ( SCH 37370; SCH37370 )

产品货号. M23344 CAS No. 117796-52-8

SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ￥1580 有现货
10MG ￥2260 有现货
25MG ￥4066 有现货
50MG ￥5897 有现货
100MG ￥7995 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
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生物学信息

  • 产品名称
    SCH-37370
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine.
  • 产品描述
    SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM).
  • 同义词
    SCH 37370; SCH37370
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    PAF
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    117796-52-8
  • 分子量
    352.9
  • 分子式
    C21H21ClN2O
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:Soluble
  • SMILES
    CC(N(CC1)CCC1=C(c(cc1)c(CC2)cc1Cl)c1c2cccn1)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Kaminski JJ, Carruthers NI, Wong SC, Chan TM, Billah MM, Tozzi S, McPhail AT. Conformational considerations in the design of dual antagonists of platelet-activating factor (PAF) and histamine. Bioorg Med Chem. 1999 Jul;7(7):1413-23. PubMed PMID: 10465415.
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