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SC-26196

CAS No. 218136-59-5

SC-26196 ( —— )

产品货号. M21997 CAS No. 218136-59-5

SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 μM in a rat liver microsomal assay, with antiinflammatory properties.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥502 有现货
5MG ¥794 有现货
10MG ¥1199 有现货
25MG ¥1993 有现货
50MG ¥2940 有现货
100MG ¥4366 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    SC-26196
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 μM in a rat liver microsomal assay, with antiinflammatory properties.
  • 产品描述
    SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 μM in a rat liver microsomal assay, with antiinflammatory properties. The FADS2 inhibitor SC26196 reduced PBMC, but not Jurkat cell, proliferation suggesting PUFA synthesis is involved in regulating mitosis in PBMCs.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    D6D
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    218136-59-5
  • 分子量
    423.55
  • 分子式
    C27H29N5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:4mg/ml (9.44 Mm; Need ultrasonic)
  • SMILES
    C1CN(CCN1CCCC(C#N)(C2=CC=CC=C2)C3=CC=CC=C3)N=CC4=CN=CC=C4
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Obukowicz MG, et al. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. J Pharmacol Exp Ther. 1998 Oct;287(1):157-66.
产品手册
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