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SC-202671
CAS No. 312917-14-9
SC-202671 ( TCS JNK 5a, TCS-JNK-5a, JNK Inhibitor IX, SC-202671 )
产品货号. M18411 CAS No. 312917-14-9
TCS JNK 5a is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥316 | 有现货 |
|
| 10MG | ￥518 | 有现货 |
|
| 25MG | ￥932 | 有现货 |
|
| 50MG | ￥1596 | 有现货 |
|
| 100MG | ￥2406 | 有现货 |
|
| 500MG | ￥5897 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称SC-202671
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述TCS JNK 5a is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
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产品描述TCS JNK 5a, also called JNK Inhibitor IX , is a selective and potent inhibitor of JNK inhibitor. Exposure of human Jurkat T cells to SC-202671 targeting JNK2 and JNK3, caused apoptotic DNA fragmentation along with G2/M arrest, phosphorylation of Bcl-2, Mcl-1, and Bim, Δψm loss, and activation of Bak and caspase cascade.
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同义词TCS JNK 5a, TCS-JNK-5a, JNK Inhibitor IX, SC-202671
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通路Others
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靶点Other Targets
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受体JNK2; JNK3
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number312917-14-9
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分子量332.42
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分子式C20H16N2OS
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纯度98%
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溶解度DMSO : ≥ 51 mg/mL; 153.42 mM
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SMILESC1CCc2c(C1)c(c(s2)NC(=O)c1cccc2ccccc12)C#N
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化学全称N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-1-naphthamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Angell RM, et al. Bioorg Med Chem Lett. 2007, 17(5), 1296-1301.2. Rudolf E, et al. Toxicol Lett. 2009, 188(3), 236-242.
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