021-51111890
购物车（）
sales@molnova.cn
SC-202671
CAS No. 312917-14-9
SC-202671 ( TCS JNK 5a, TCS-JNK-5a, JNK Inhibitor IX, SC-202671 )
产品货号. M18411 CAS No. 312917-14-9
TCS JNK 5a is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥316 | 有现货 |
|
| 10MG | ￥518 | 有现货 |
|
| 25MG | ￥932 | 有现货 |
|
| 50MG | ￥1596 | 有现货 |
|
| 100MG | ￥2406 | 有现货 |
|
| 500MG | ￥5897 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称SC-202671
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述TCS JNK 5a is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
-
产品描述TCS JNK 5a, also called JNK Inhibitor IX , is a selective and potent inhibitor of JNK inhibitor. Exposure of human Jurkat T cells to SC-202671 targeting JNK2 and JNK3, caused apoptotic DNA fragmentation along with G2/M arrest, phosphorylation of Bcl-2, Mcl-1, and Bim, Δψm loss, and activation of Bak and caspase cascade.
-
同义词TCS JNK 5a, TCS-JNK-5a, JNK Inhibitor IX, SC-202671
-
通路Others
-
靶点Other Targets
-
受体JNK2; JNK3
-
研究领域Inflammation/Immunology
-
适应症——
化学信息
-
CAS Number312917-14-9
-
分子量332.42
-
分子式C20H16N2OS
-
纯度98%
-
溶解度DMSO : ≥ 51 mg/mL; 153.42 mM
-
SMILESC1CCc2c(C1)c(c(s2)NC(=O)c1cccc2ccccc12)C#N
-
化学全称N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-1-naphthamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Angell RM, et al. Bioorg Med Chem Lett. 2007, 17(5), 1296-1301.2. Rudolf E, et al. Toxicol Lett. 2009, 188(3), 236-242.
产品手册
关联产品
-
AER-271
AER-271 (AER271) is a selective, small molecule inhibitor of aquaporin-4 (AQP4), the prodrug of AER-270 with enhanced solubility.
-
p-Hydroxybenzaldehyd...
4-Hydroxybenzaldehyde shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity.
-
Justicidin C(Neojust...
Justicidin C is an antiviral lignan. Justicidin C shows strong antiviral activity against vesicular stomatitis virus and low cytotoxicity against rabbit lung cells (RL-33) .
