SBC-115076

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

SBC-115076 是一种有效的细胞外前蛋白转化酶枯草杆菌蛋白酶 9 型 (PCSK9) 拮抗剂。

SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.

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Animal Model:Female Wistar rats (high-fat diet (HFD)- fed) Dosage:4 mg/kg Administration:S.c.; daily for 3 weeks Result:Superior to atorvastatin in instigating weight loss, cholesterol reduction, and attenuation of mitochondrial oxidative stress in oxidative muscle fibers of obese female rats.

SBC-115076 | SBC 115076 | SBC115076.

Tyrosine Kinase

Src

PCSK9

Cardiovascular Disease

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489415-96-5

527.61

C31H33N3O5

>98% (HPLC)

DMSO : ≥ 32 mg/mL; 60.65 mM

Cc1cc(C(=O)C2=C(O)C(=O)N(C2c2ccncc2)CCCN2CCOCC2)ccc1OCc1ccccc1

4-(4-(benzyloxy)-3-methylbenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one

(-20℃)

With Ice Pack

≥ 2 years