SB-505124 ( SB505124; SB-505124; SB 505124 )

产品货号. M15656 CAS No. 694433-59-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

SB-505124
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM in cell-free assays, respectively, also inhibits ALK7, but does not inhibit ALK1, 2, 3, or 6.
产品描述

SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM in cell-free assays, respectively, also inhibits ALK7, but does not inhibit ALK1, 2, 3, or 6.
同义词

SB505124; SB-505124; SB 505124
通路

Angiogenesis
靶点

ALK
受体

ALK4; ALK5
研究领域

Cancer
适应症

——

CAS Number

694433-59-5
分子量

335.40
分子式

C20H21N3O2
纯度

>98%(HPLC)
溶解度

Ethanol: 67 mg/mL (199.76 mM); DMSO: 67 mg/mL (199.76 mM)
SMILES

CC1=CC=CC(C2=C(C3=CC=C(OCO4)C4=C3)N=C(C(C)(C)C)N2)=N1
化学全称

2-(4-(benzo[d][1,3]dioxol-5-yl)-2-(tert-butyl)-1H-imidazol-5-yl)-6-methylpyridine

1. DaCosta Byfield S, et al. Mol Pharmacol. 2004, 65(3), 744-752.

计算器

产品手册

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