S-Gboxin ( —— )

产品货号. M20091 CAS No. 2101317-21-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

S-Gboxin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

S-Gboxin 是 Gboxin 的活性类似物，具有有效的抗肿瘤活性。 S-Gboxin 抑制小鼠和人胶质母细胞瘤的生长（GBM，IC50：470 nM）。
产品描述

S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits the growth of mouse and human glioblastoma (GBM IC50: 470 nM).
体外实验

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体内实验

S-Gboxin retains excellent metabolic stability, enhanced plasma stability, and PK-propertiessuitable for in vivo studies. S-Gboxin (10 mg/kg/day; intraperitoneally) inhibits glioblastoma (GBM) growth in vivo. Animal Model:Female nude mice (6 to 9 weeks)Dosage:10 mg/kg/day Administration:Administered intraperitoneally; daily; 3 or 14 days Result:Resulted in significant attenuation of growth and decreased cellular density compared to controls.
同义词

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通路

Others
靶点

Other Targets
受体

Others
研究领域

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适应症

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CAS Number

2101317-21-7
分子量

600.46
分子式

C27H32F3IN2O2
纯度

>98% (HPLC)
溶解度

DMSO: 85 mg/mL (141.56 mM)
SMILES

[I-].CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)Cn1c(-c2cccc(c2)C(F)(F)F)[n+](C)c2ccccc12
化学全称

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