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S-Gboxin
CAS No. 2101317-21-7
S-Gboxin ( —— )
产品货号. M20091 CAS No. 2101317-21-7
S-Gboxin 是 Gboxin 的活性类似物，具有有效的抗肿瘤活性。 S-Gboxin 抑制小鼠和人胶质母细胞瘤的生长（GBM，IC50：470 nM）。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1936 | 有现货 |
|
| 10MG | ￥2811 | 有现货 |
|
| 25MG | ￥4771 | 有现货 |
|
| 50MG | ￥6820 | 有现货 |
|
| 100MG | ￥9396 | 有现货 |
|
| 500MG | ￥18873 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称S-Gboxin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述S-Gboxin 是 Gboxin 的活性类似物，具有有效的抗肿瘤活性。 S-Gboxin 抑制小鼠和人胶质母细胞瘤的生长（GBM，IC50：470 nM）。
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产品描述S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits the growth of mouse and human glioblastoma (GBM IC50: 470 nM).
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体外实验——
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体内实验S-Gboxin retains excellent metabolic stability, enhanced plasma stability, and PK-propertiessuitable for in vivo studies. S-Gboxin (10 mg/kg/day; intraperitoneally) inhibits glioblastoma (GBM) growth in vivo. Animal Model:Female nude mice (6 to 9 weeks)Dosage:10 mg/kg/day Administration:Administered intraperitoneally; daily; 3 or 14 days Result:Resulted in significant attenuation of growth and decreased cellular density compared to controls.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number2101317-21-7
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分子量600.46
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分子式C27H32F3IN2O2
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纯度>98% (HPLC)
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溶解度DMSO: 85 mg/mL (141.56 mM)
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SMILES[I-].CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)Cn1c(-c2cccc(c2)C(F)(F)F)[n+](C)c2ccccc12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Shi Y et al. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. 2019 Mar;567(7748):341-346.
产品手册
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