Rilematovir ( JNJ-678; JNJ-53718678 )

产品货号. M26723 CAS No. 1383450-81-4

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产品名称

Rilematovir
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

JNJ-678 is a novel inhibitor of the fusion protein. JNJ-678 shows the potential for respiratory syncytial virus (RSV) treatment.
产品描述

JNJ-678 is a novel inhibitor of the fusion protein. JNJ-678 shows the potential for respiratory syncytial virus (RSV) treatment.(In Vitro):Rilematovir is highly active against a number of RSV strains from both A and B subtypes, especially the A2 strain. The EC50 of HeLa cells is 460?pM.(In Vivo):Rilematovir efficiently suppresses established acute lower respiratory tract infection in the animals after oral treatment of neonatal lambs with Rilematovir, or with an equally active close analog.
同义词

JNJ-678; JNJ-53718678
通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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1.Azevedo RDS, et al. Effects of pyriproxyfen on zebrafish brain mitochondria and acetylcholinesterase. Chemosphere. 2021 Jan;263:128029.

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