Ribocil ( Ribocil )

产品货号. M11578 CAS No. 1381289-58-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Ribocil
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Ribocil is a synthetic mimic of riboflavin 5’-monophosphate (FMN) that competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB.
产品描述

Ribocil is a synthetic mimic of riboflavin 5’-monophosphate (FMN) that competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB; depletes cellular levels of riboflavin with an IC50 value of 0.3 μM and inhibits E. coli growth with an MIC value of 2 ug/ml.
同义词

Ribocil
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibacterial
研究领域

Infection
适应症

——

CAS Number

1381289-58-2
分子量

382.48
分子式

C19H22N6OS
纯度

>98% (HPLC)
溶解度

10 mM in DMSO
SMILES

CNC1=NC=C(C=N1)CN2CCCC(C2)C3=NC(=CC(=O)N3)C4=CC=CS4
化学全称

4(3H)-Pyrimidinone, 2-[1-[[2-(methylamino)-5-pyrimidinyl]methyl]-3-piperidinyl]-6-(2-thienyl)-

1. Howe JA, et al. Nature. 2015 Oct 29;526(7575):672-7.
2. Hermann T. Nature. 2015 Oct 29;526(7575):650-1.

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