Resibufogenin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system.

Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction. Resibufogenina's major metabolic pathway in the human liver is CYP3A4 dominantly mediated 5β-hydroxylation .

RBG; Bufotenine; Resibufogenin

Angiogenesis

PDE

Others

Cancer

——

465-39-4

384.51

C24H32O4

98%

DMSO : 100 mg/mL 260.07 mM;

CC12CCC(CC1CCC3C2CCC4(C35C(O5)CC4C6=COC(=O)C=C6)C)O

14,15beta-Epoxy-3beta-hydroxy-5beta-bufa-20,22-dienolide

(-20℃)

With Ice Pack

≥ 2 years