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Radezolid

CAS No. 869884-78-6

Radezolid ( RX-1741 )

产品货号. M26804 CAS No. 869884-78-6

Radezolid 是一种新型恶唑烷酮类抗生素。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1353 有现货
10MG ¥2292 有现货
25MG ¥3912 有现货
50MG ¥5597 有现货
100MG ¥7962 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Radezolid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Radezolid 是一种新型恶唑烷酮类抗生素。
  • 产品描述
    Radezolid is a novel oxazolidinone antibiotic agent.(In Vitro):Radezolid displays a greater potency than linezolid, independent of the bacteria tested, when concentrations are expressed on a weight (mg/L) basis. Radezolid shows an improved potency compared to that of linezolid when concentrations are expressed on a weight (mg/L) basis. Radezolid MICs are systematically equal to or lower (up to 3 log2 dilutions) than those of linezolid for all linezolid-susceptible strains, with an 8-fold difference for the linezolid-resistant strains. Radezolid and TR-700 perform well against 3-copy G2447T, G2576T, and G2576T/T2571C mutants .
  • 体外实验
    Radezolid MICs are systematically equal to or lower (up to 3 log2 dilutions) than those of linezolid for all linezolid-susceptible strains, with an 8-fold difference for the linezolid-resistant strains. Radezolid shows a greater potency than linezolid, independent of the bacteria tested, when concentrations are expressed on a weight (mg/L) basis. Radezolid shows an improved potency compared to that of linezolid when concentrations are expressed on a weight (mg/L) basis. Radezolid and TR-700 perform well against 3-copy G2447T, G2576T, and G2576T/T2571C mutants.
  • 体内实验
    ——
  • 同义词
    RX-1741
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    TNIK
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    869884-78-6
  • 分子量
    438.463
  • 分子式
    C22H23FN6O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : ≥ 25 mg/mL (57.02 mM)
  • SMILES
    CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(c(F)c1)-c1ccc(CNCc2cnn[nH]2)cc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Lee Y, et al. Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells. Oncotarget. 2017 Jun 20;8(25):41091-41101.
产品手册
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