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RRX-001
CAS No. 925206-65-1
RRX-001 ( RRX001;RRX 001 )
产品货号. M16629 CAS No. 925206-65-1
RRX-001 (RRX001) is a novel NO and hypoxia mediated anticancer agent with with epigenetic and immunologic activity.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥567 | 有现货 |
|
| 5MG | ￥948 | 有现货 |
|
| 10MG | ￥1256 | 有现货 |
|
| 25MG | ￥2373 | 有现货 |
|
| 50MG | ￥4155 | 有现货 |
|
| 100MG | ￥6059 | 有现货 |
|
| 500MG | ￥12636 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称RRX-001
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述RRX-001 (RRX001) is a novel NO and hypoxia mediated anticancer agent with with epigenetic and immunologic activity.
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产品描述RRX-001 (RRX001) is a novel NO and hypoxia mediated anticancer agent with with epigenetic and immunologic activity; targets CD133 + /CD44 + cancer stem cells from colon cancer cell-lines, HT-29, Caco-2, and HCT116, and inhibits Wnt pathway signalling with downregulation of c-Myc; inhibits HCT 116 and decreases levels of the DNA methyltransferases DNMT1 and DNMT3a in a time and dose-dependent manner; RRX-001 (RRX001) is a chemosensitizer in multiple tumor types and disease states including malaria, hemorrhagic shock and sickle cell anemia.Lung Cancer Phase 2 Clinical
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同义词RRX001;RRX 001
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Cancer
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适应症Lung Cancer
化学信息
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CAS Number925206-65-1
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分子量268.02
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分子式C5H6BrN3O5
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 100 mg/mL 373.11 mM
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SMILESO=[N+](C1([N+]([O-])=O)CN(C(CBr)=O)C1)[O-]
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化学全称2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Reid T, et al. Lancet Oncol. 2015 Sep;16(9):1133-1142. doi: 10.1016/S1470-2045(15)00089-3.
2. Scicinski J, et al. Redox Biol. 2015 Aug;5:422. doi: 10.1016/j.redox.2015.09.035.
3. Kim MM, et al. Transl Oncol. 2016 Apr;9(2):108-113.
4. Oronsky B, et al. Invest New Drugs. 2016 Jun;34(3):371-7.
2. Scicinski J, et al. Redox Biol. 2015 Aug;5:422. doi: 10.1016/j.redox.2015.09.035.
3. Kim MM, et al. Transl Oncol. 2016 Apr;9(2):108-113.
4. Oronsky B, et al. Invest New Drugs. 2016 Jun;34(3):371-7.
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