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Quercetagetin
CAS No. 90-18-6
Quercetagetin ( 6-Hydroxyquercetin )
产品货号. M21534 CAS No. 90-18-6
槲皮素（6-羟基槲皮素）是从温州柑橘中分离出来的主要黄酮类化合物。它是一种中等效力、选择性、细胞渗透性 pim-1 激酶抑制剂 (IC50: 0.34 μM)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1725 | 有现货 |
|
| 10MG | ￥2576 | 有现货 |
|
| 25MG | ￥4342 | 有现货 |
|
| 50MG | ￥6253 | 有现货 |
|
| 100MG | ￥8505 | 有现货 |
|
| 500MG | ￥16929 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Quercetagetin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述槲皮素（6-羟基槲皮素）是从温州柑橘中分离出来的主要黄酮类化合物。它是一种中等效力、选择性、细胞渗透性 pim-1 激酶抑制剂 (IC50: 0.34 μM)。
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产品描述Quercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).
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体外实验Cell Viability Assay Cell Line:RWPE2 prostate cancer cells Concentration:0.1, 1, 10, and 100 μM Incubation Time:72 hours Result:Inhibited growth of RWPE2 prostate cancer cells with average ED50 is 3.8 μM.
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体内实验Animal Model:SKH-1 hairless mice modelDosage:4 or 20 nmol Administration:Topical application; 28 weeks Result:Inhibited UVB-induced skin tumorigenesis in SKH-1 hairless mice models. Delayed the development of tumors and reduced tumor volumes in an SKH-1 hairless mice model.
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同义词6-Hydroxyquercetin
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通路JAK/STAT Signaling
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靶点Pim
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受体Pim1
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研究领域——
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适应症——
化学信息
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CAS Number90-18-6
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分子量318.23
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分子式C15H10O8
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纯度>98% (HPLC)
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溶解度DMSO:125 mg/mL (392.79 mM)
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SMILESOc(ccc(C(Oc(c(C1=O)c2O)cc(O)c2O)=C1O)c1)c1O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Yang X et al. Isolation and identification of an antioxidant flavonoid compound from citrus-processing by-product. J Sci Food Agric. 2011 Aug 15;91(10):1925-7.
