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Pyridaben
CAS No. 96489-71-3
Pyridaben ( —— )
产品货号. M19913 CAS No. 96489-71-3
Pyridaben 是一种 METI 杀螨剂，可抑制复合物 I 的线粒体电子传递（METI；大鼠脑线粒体中 Ki = 0.36 nmol/mg 蛋白质）。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ￥332 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Pyridaben
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Pyridaben 是一种 METI 杀螨剂，可抑制复合物 I 的线粒体电子传递（METI；大鼠脑线粒体中 Ki = 0.36 nmol/mg 蛋白质）。
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产品描述Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; Ki = 0.36 nmol/mg protein in rat brain mitochondria).
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体外实验Cell Viability Assay Cell Line:Rat brain submitochondrial particles Concentration:0-10 μM Incubation Time:3 min Result:Led to a decrease of NADH-cytochrome reductase activity (complex I-III) and without modification of succinate-cytochrome c reductase activity (complex II-III) and of cytochrome oxidase activity (complex IV)Cell Viability Assay Cell Line:Rat brain mitochondriaConcentration:0-10 μMIncubation Time:3 min Result:Showed a marked and dose-dependent decrease in respiratory control in the presence of malate-glutamate as substrate (IC50=1.7 μM)
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体NADH dehydrogenase(NADH:ubiquinone oxidoreductase|Electron transport complex I)
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研究领域——
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适应症——
化学信息
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CAS Number96489-71-3
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分子量364.93
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分子式C19H25ClN2OS
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纯度>98% (HPLC)
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溶解度DMSO: 50 mg/mL;Ethanol: 57 mg/mL;Water: Insoluble
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SMILESCC(C)(C)c1ccc(CSc2cnn(c(=O)c2Cl)C(C)(C)C)cc1
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化学全称2-(tert-butyl)-5-((4-(tert-butyl)benzyl)thio)-4-chloropyridazin-3(2H)-one
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Navarro A et al. Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity. J Bioenerg Biomembr. 2010 Oct;42(5):405-12.
