
Psoralidin
CAS No. 18642-23-4
Psoralidin ( Psoralidin )
产品货号. M18153 CAS No. 18642-23-4
Psoralidin 抑制 Akt 磷酸化和磷脂酰肌醇 3-激酶激活和转录。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥462 | 有现货 |
![]() ![]() |
10MG | ¥786 | 有现货 |
![]() ![]() |
25MG | ¥1426 | 有现货 |
![]() ![]() |
50MG | ¥2122 | 有现货 |
![]() ![]() |
100MG | ¥3151 | 有现货 |
![]() ![]() |
500MG | ¥7152 | 有现货 |
![]() ![]() |
1G | 获取报价 | 有现货 |
![]() ![]() |
生物学信息
-
产品名称Psoralidin
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Psoralidin 抑制 Akt 磷酸化和磷脂酰肌醇 3-激酶激活和转录。
-
产品描述Psoralidin is a metabolic product from the seed of psoraleacorylifolia, possessing anti-inflammatory and immunomodulatory effects. Psoralidin inhibits lipopolysaccharide induced bone resorption by suppressing the inflammatory cytokines: TNF-α and IL-6 expression, as well as the ratio of RNAKL : OPG.
-
体外实验Cell Viability Assay Cell Line:ALDH- cells, ALDH+ cells, commercial breast cancer stem cells (BSCSs), and normal breast epithelial cells (MCF-12A) Concentration:10, 15, 50, and 25 μM Incubation Time:24?hours Result:IC50s of 18 to 21?μM for ALDH- cells, ALDH+ cells, commercial BCSCs. Apoptosis Analysis Cell Line:ALDH- cells, ALDH+ cells, and commercial BCSCs Concentration:20?and 30 μM Incubation Time:24?hours Result:No significant induction of apoptosis was observed for any of the three cell types following treatment at 20?μM. However, 53.60%, 44.1%, and 45.9% of cells were apoptotic at 30?μMin ALDH- cells, ALDH+ cells, and commercial BCSCs, respectively.
-
体内实验Animal Model:BALB/c mice Dosage:5 mg/kg Administration:Intraperitoneal application; 30 min before and 1 h after IR irradiation (20 Gy).Result:Anti-inflammatory effect in IR-irradiated mice.
-
同义词Psoralidin
-
通路Others
-
靶点Other Targets
-
受体Akt| Phosphatidylinositol 3-kinase
-
研究领域Others-Field
-
适应症——
化学信息
-
CAS Number18642-23-4
-
分子量336.34
-
分子式C20H16O5
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO : 50 mg/mL (148.66 mM)
-
SMILESCC(=CCc1c(cc2c(c1)c1c(c3c(o1)cc(cc3)O)c(=O)o2)O)C
-
化学全称3,9-Dihydroxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Sun H, et al. J Pharm Sci. 2015 Jul;104(7):2369-77.
产品手册




关联产品
-
Cyclopentadecanone
环十五酮 用于香料(麝香气味)。
-
Sakamototide substra...
Sakamototide substrate peptide TFA is a peptide substrate of AMPK kinase family and can be used for the determination of kinase activity.
-
Isokaempferide 7-rut...
The herbs of Centaurea arbutifolia.