
Protodioscin
CAS No. 55056-80-9
Protodioscin ( —— )
产品货号. M18789 CAS No. 55056-80-9
原薯蓣皂苷是薯蓣根茎中的主要甾体皂苷,具有抗高脂血症、抗癌特性。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥512 | 有现货 |
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10MG | ¥864 | 有现货 |
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25MG | ¥1746 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Protodioscin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述原薯蓣皂苷是薯蓣根茎中的主要甾体皂苷,具有抗高脂血症、抗癌特性。
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产品描述Protodioscin is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties.
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体外实验——
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体内实验Protodioscin (5 and 10 mg/kg) significantly improves glucose intolerance and reduced the levels of serum UA, BUN, Cr, TC and TG. Protodioscin significantly reduces renal concentrations of IL-1β, IL-6 and TNF-α by inhibiting the activation of nuclear factor-κB, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase and extracellular signal-regulated kinase. Protodioscin ameliorates the death rate, inhibits the increase in neurological deficit scores and infarct volume, and reduces the apoptotic nerve cells induced by MCAO in rats. Protodioscin attenuates the change of relevant apoptins, suppresses the release of pro-inflammatory cytokines in serum and reverses the protein expression of NF-κB (in nucleus and cytoplasm) and IκBα (in cytoplasm) induced by MCAO in rats. Protodioscin (0.5 mg/kg, i.p.) increases the coagulation time by appr 50?% as compared to that of high-fat diet control rats. Protodioscin possesses a promising effect in lowering the blood levels of both lipoproteins, especially LDL, thus resulting in a high ratio of HDL/LDL.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域Cancer
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适应症——
化学信息
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CAS Number55056-80-9
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分子量1049.21
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分子式C51H84O22
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : 50 mg/mL (47.66 mM)
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SMILESC[C@H]1[C@H]2[C@H](C[C@@H]3[C@@]2(CC[C@H]2[C@H]3CC=C3[C@@]2(CC[C@@H](C3)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O)O)O)O)O[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O)O)O)C)C)O[C@@]1(CC[C@@H](C)CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Wang T1, Choi RC, Li J, Li J,et al.Antihyperlipidemic effect of protodioscin, an active ingredient isolated from the rhizomes of Dioscorea nipponica.Planta Med. 2010 Oct;76(15):1642-6.
产品手册




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